Endocrine Abstracts

Introduction: Non-celiac gluten sensitivity (NCGS) belongs to gluten-related disorders. Patients with NCGS develop a variety of intestinal and/or extraintestinal symptoms such as abdominal pain, bloating, bowel habit abnormalities, nausea, gastroesophageal reflux disease and aphthous stomatitis, that improve when gluten is removed from the diet. The diagnosis is made after exclusion of coeliac disease and wheat allergy. Although thyroxine malabsorption has been described in pa...

Background: Diabetic ketoacidosis (DKA) has been associated with severe hemolysis in patients with Glucose-6-phosphate dehydrogenase (G6PD) deficiency after restoration of euglycemia. Less than 30 cases have been reported so far. The exact mechanism is not fully understood.Case presentation: A 35-year-old African American man presented to the emergency department with polyuria, polydipsia, abdominal pain and weight loss the last 15 days. Physical examina...

Introduction: Mutations in the variable number of tandem repeats (VNTR) region of the carboxyl-ester lipase (CEL) gene can cause a very rare type of maturity-onset diabetes of the young (MODY 8) characterized by insulinopenic diabetes mellitus (DM) in early adulthood and slowly progressive exocrine pancreatic dysfunction. We present the unusual case of a patient with heterozygosity in a variant of CEL outside the VNTR region suffering from DM, dyslipidemia and exocrin...

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with multisystem involvement and varied presentation but its association with adrenal insufficiency is rarely reported.Case presentation: A 30-year-old female presented to the emergency department with fever, lethargy and syncopal episodes during the last 48 h. She complained of general weakness, abdominal pain, nausea, vomiting, weight loss and anorexia for five months. Symptoms det...

Aim: To explore the epidemiological characteristics and symptoms of psychological distress of well-controlled endocrine patients without a diagnosis of a psychiatric disorder attending the Endocrine outpatient clinic of the University Hospital, Heraklion, Crete, Greece during the COVID-19 pandemic. Methods: Eighty-four patients participated by completing questionnaires about demographics, endocrine diagnosis, covid infection, preventive measures, vaccination s...

Background: Psychological distress is elevated during pandemics such as the COVID-19 outbreak both in health care professionals and patients.Aim: To compare worries about the COVID-19 pandemic, need and sources of information, and psychological distress between endocrinology patients and staff at an outpatient department of the University Hospital, Heraklion, Crete, GreeceMethods: One hundred and four patients and sixty members of ...

Introduction: Pheochromocytomas (PHEOs) are rare catecholamine-producing tumors with metastatic potential. Composite PHEOs are rare (3% of adrenal tumors) including components other than adrenal chromaffin cells. We report a case of a rare composite neoplasm with a very rapid disease progression.Case report: A 57-year-old male was referred to the Endocrinology Department for investigation of a retroperitoneal mass. He presented with nonspecific symptoms ...

Background: Psychological distress is elevated during pandemics such as the COVID-19 outbreak. Patients with diabetes mellitus (DM), are a particularly vulnerable risk group. However, data of the impact of other endocrinopathies on psychological status of patients during pandemics are lacking so far.Aim: To compare psychological distress about COVID-19 pandemic, between endocrine patients with a variety of endocrinopathies and patients with non-endocrine...